Our group discovered an unprecedented, evolutionary conserved core purine enzyme (FAMIN) that prevents inflammation and autoimmunity. Genetic loss of function causes monogenic Still's disease (a childhood fever syndrome with arthritis) and Crohn's disease (an inflammatory bowel disease), and a common hypomorphic variant predisposes for Crohn's disease and leprosy (a chronic infection). Cader et al, Cell 2020 Jan 23, DOI 10.1016/j.cell.2019.12.017 and Saveljeva et al, Cell Metab 2022 Jan 4, DOI 10.1016/j.cmet.2021.12.009
We are looking for an enthusiastic, talented structural biologist, who shares our passion for discovery and who is looking for an exciting challenge within our highly multidisciplinary group.
Our lab is located in the new Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), for more info, see https://www.citiid.cam.ac.uk and http://www.med.cam.ac.uk/kaser/.
The initial employment contract is for one year, with the intention for extension, contingent on available funding.
For informal inquiries please contact Professor Arthur Kaser FMedSci (ak729@cam.ac.uk).
Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Closing date: 2nd February 2025
Interview Date: to be confirmed
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.
For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data )on our HR web pages.
Please quote reference RC44760 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.