The Milner Therapeutics Institute (MTI) at the University of Cambridge aims to accelerate translation of pioneering science into therapies. The newly established Functional Genomics Screening Laboratory (FGSL) at the MTI applies arrayed CRISPR screening in human cellular models to advance mechanistic understanding underlying tissue homeostasis and disease biology. Formed as a joint venture with the Medical Research Council and AstraZeneca, this new laboratory aligns with the MTI's vision of breaking the mould of how academia and industry interact. The FGSL is part of the UK Research and Innovation's Human Functional Genomics Initiative to facilitate innovative and collaborative research to drive new scientific discoveries.
We are seeking to recruit a scientist with experience in high-content imaging, both in the wet and dry lab, to join the FGSL team. You will be applying your expertise to design, implement and interpret arrayed CRISPR screens with imaging as well as other phenotypic endpoints. The ideal candidate will be proficient in a range of imaging assays such as fixed or live imaging, Cell Painting, and RNA imaging to identify key phenotype suitable for high-throughput screening. Previous experience in characterising complex models such as 3D or co-cultures using microscopy approaches is desirable. Programming experience in processing and analysing bioimage data is highly desirable.
This is a collaborative role where you will work closely with scientists and bioinformaticians from the MTI, AstraZeneca, small/medium enterprises and academic institutions. You will have the opportunity to develop new skills in areas including multi-modality screens, automation platform and complex model culture.
The MTI is a buoyant, vibrant and fast-paced environment and is ideal for those who thrive in the face of change. We welcome applications from recent PhD graduates or experienced postdocs that are enthusiastic to work as part of a dynamic team at the interface between academia and industry. We offer an engaging and supportive environment that fosters professional growth and career development.
DEPARTMENT/LOCATION
Milner Therapeutics Institute, Cambridge
SALARY
Grade 7 (£36,024-£44,263)
REFERENCE
PR43931