Senior Scientist – (Analytical lead)
Type: Permanent
Location: Macclesfield
Competitive salary and Benefits
Introduction to role:
Join AstraZeneca, a global, innovation-driven biopharmaceutical company where we focus on the discovery, development and delivery of life-saving medicines. We are committed to sustainability and minimizing our environmental impact. We are proud to foster a culture that inspires innovation and collaboration. We empower our colleagues to express diverse perspectives and feel valued, respected and rewarded for their ideas and creativity. We now have an exciting opportunity for a Senior Scientist in our growing analytical development teams.
Accountabilities:
As an analytical scientist, you will work closely with process chemists, engineers, project managers and other scientists. You will contribute to pharmaceutical development programmes, supporting project progression through late clinical development and launch. You may lead significant parts of analytical development programmes, directing the work of other scientists. Your role will involve leading API analytical activities, developing API analytical control strategies, identifying and solving potential analytical project issues, planning and conducting lab-based experimental work, supporting the technical development of other scientists, collaborating with internal and external manufacturing partners, keeping abreast of scientific developments and authoring the CMC components of regulatory submissions.
Essential Skills/Experience:
A degree (BSc, MSc or equivalent) in Chemistry or Analytical Chemistry/Science with a proven track record of analytical development in a pharmaceutical environment, or a PhD including aspects of analytical measurement.
Knowledge and practical experience across a range of analytical techniques, e.g. LC, MS, GC, NMR.
Scientific leadership skills and the ability to use knowledge and experience to assess options available and deliver robust scientific contributions to projects.
Strong problem-solving skills, underpinned by strong practical laboratory experience.
Experience of working collaboratively within a mixed skill technical team and ability to develop and utilise networks.
Ability to communicate complex scientific information in a clear, concise and understandable way.
Desirable Skills/Experience:
Previous experience in analytical methods development and validation for the analysis of peptides API.
Familiarity with methods and instruments used for peptides analysis such as HPLC (SEC, RP, IEX, HILIC), FTIR, SEC-MALS and mass spec.
Understanding of typical impurity types formed during peptide API manufacture and storage, and suitable analytical controls.
Knowledge and practical experience of quality and regulatory requirements (GMP and ICH), and good SHE practices.
Strong influencing, planning and prioritisation skills to ensure project delivery to deadlines.
Experience of leading technical teams, coaching and people development.
Ability to lead improvement projects confidently and successfully.
Commitment to continuous improvement and innovation, and knowledge of Lean principles.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca, we are driven by our commitment to deliver accelerated growth for AstraZeneca and to make people's lives better. It pushes us to keep building on our foundations and progressing as we turn our ever-growing and increasingly complex pipeline from molecule to medicine. Be part of evolving how we work with Lean, cutting-edge science, digitalisation and sustainable practices. We are an inclusive community that supports each other on our journeys. We are intellectually stimulated by constant learning. There's potential for multiple, global careers and great rewards, for those who embrace the diverse opportunities.
Are you ready to make a positive impact in a team where it means more? Apply now and join us in our mission to deliver more medicines to patients, quicker and more affordably.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.