Senior Scientist, Flow Cytometry

AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.

Senior Research Scientist, Flow Cytometry

Cambridge, UK

Competitive salary & benefits

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe. As a part of our Dynamic Omics team, you’ll play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives.

The Flow Cytometry group is part of Dynamic Omics/Centre of Genomics Research (CGR)/Discovery Sciences (DS) within AstraZeneca and works across all therapeutic areas. The team delivers key data to projects across all phases of the drug discovery and development, and we work with all modalities from small molecules to biologics. The Flow Cytometry Centre of Excellence has state-of-the-art instrumentation with cutting edge technology and associated expertise.

What you’ll do

You will work closely with specialists in Early and Translational Oncology, drug discovery, pre-clinical modelling, and clinical development. In this role you will be responsible for designing and implementing novel immunology/flow cytometry assays and data pipeline, develop new immunological technologies, and extensively collaborate with all the departments within Oncology.

Examples of typical tasks:

  • Design and implement flow cytometry based immune technologies and support the flow core needs
  • Make detailed observations, analyse data, interpret results, and exercise appropriate technical discretion in the design, execution, and interpretation of experimental results in an independent manner
  • Establish collaboration across all the departments within Oncology
  • Maintaining a well-developed knowledge of tumour immunology and technical advances in the international community 
  • Present novel results to top tier flow cytometry and/or tumour immunology conferences and publish in high impact journals 
  • Ensuring own work, and work of team, is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other internal AstraZeneca standards and external regulations. 

Essential Criteria

  • Ph.D. in Immunology, Immuno-Oncology, Cell Biology, Bioinformatics or other related scientific field, or a Bachelor’s/Masters with 5+ years of directly relevant outstanding performance
  • Strong hands-on skills in basic biochemical and immunological methods including multi-colour flow cytometry, ELISA/multiplex assays, ELISPOT, western blotting, immunoprecipitation, cell killing assays
  • Extensive experience in multi-colour flow cytometry and with complex data analysis software such as FlowJo and FCS Express
  • Extensive experience in human and/or murine immunology
  • Ability to communicate effectively with team members and non-experts, both verbally and through documentation 
  • Excellent interpersonal skills and willingness to work within a team in a quickly evolving environment 

Desirable Criteria

Experience in developing web interfaces with Dash, Shiny App or equivalent packages is highly desirable

  • Strong programming skills such as Python, R and Java, and in open-source ML packages (e.g. scikit-learn, RAPIDS CUDA) is highly desirable
  • Experience with cell sorting is desirable
  • Experience in spectral and mass cytometry is desirable
  • Experience in automation and robotics
  • Postdoctoral experience in leading projects 
  • Experience in advanced flow cytometry data analysis with Cytobank and/or Omiq is a plus 

Why AstraZeneca

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

AZ Cambridge

An exciting bioscience hotspot, Cambridge is home to one of AstraZeneca’s three strategic, global R&D Centres, alongside Gothenburg and Gaithersburg. Over 3,600 employees work from our various sites across Cambridge and our offices are internationally renowned for attracting high performers, including several Nobel prize winners.

Currently based at our Darwin building on the Cambridge Science Park, the Functional Genomics team are excited for their pending relocation to our brand new, state-of-the-art R&D facility, which was officially un-veiled in November 2021, by His Royal Highness, The Prince of Wales.

The Discovery Centre (DISC), located at the heart of the Cambridge Biomedical Campus, is designed to play a central role in our mission to deliver life-changing medicines to patients. As our largest research and development centre in the UK, it will have more than 2,000 people working across therapy areas and drug discovery and development once fully occupied.

Find out more about our Cambridge campus and the DISC, here:

Why AstraZeneca

There are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork to our cutting-edge innovations – it’s a place for lifelong learning. Ultimately, it’s more than a job. We know that our work impacts people with serious conditions, many of whom have no other alternatives. That’s what drives us – the potential to impact over one billion patients worldwide.

So, what’s next?

Please complete your application before the below closing date.

We welcome your application no later than Friday, 29th July 2022.

Where can I find out more

Check out our landing page for more information on our BPD group

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