We are looking for a talented and motivated postdoctoral scientist to join the lab of Professor Sir Steve Jackson (https://www.stevejacksonlab.org/), based in the internationally renowned Cancer Research UK Cambridge Institute https://www.cruk.cam.ac.uk/, located on the Cambridge Biomedical Campus, Cambridge, UK.
DNA in our cells is frequently subject to a wide array of molecularly distinct forms of damage. To cope with this, life has evolved multiple DNA repair and associated processes, collectively termed the DNA-damage response (DDR). While considerable progress has been made in identifying DDR components and their regulators, much remains to be learned about how they operate and are controlled.
We are seeking candidates who can build on successful recent work in our laboratory to:
The work will be multi-disciplinary, combining recently established genome engineering and genetic screening approaches in human or mouse cells with next-generation sequencing, bioinformatics, cell biology, molecular biology and biochemistry.
Funds are limited (1 year in the first instance) so we are particularly keen to hear from candidates who have recently or are about to gain their PhD and wish to develop in a well-established, well-resourced DDR lab. Full support will be provided for candidates wishing to apply for their own fellowship.
Essential criteria
Candidates are expected to be largely independent and highly motivated and must have a PhD in biological sciences or be close to completing their postgraduate degree. Candidates should have strong experience in mammalian cell biology and CRISPR-based gene editing technologies. While projects in the lab benefit from access to expert bioinformaticians within the group, some knowledge of bioinformatics is desirable. Applicants should have excellent written and spoken English communication skills and demonstrate excellent organisation.
You will play key roles in a highly collaborative research programme, within the context of a large, vibrant and interactive research group, so a collaborative, friendly and collegial attitude is essential.
Please send applications in the following format: a CV; the names and contact details of two or three referees; and a one to two-page cover letter explaining why you wish to be considered for the post, an outline project, and your laboratory experience to date. Please do not send academic certificates at this stage.
Fixed-term: The funds for this post are available for 1 year in the first instance.
The closing date for applications is Friday 8th November, with interviews expected to take place shortly after this date.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38, £32,982) moving to Research Associate (Grade 7) upon confirmation of their PhD award.
If you have any queries regarding the application process or queries relating to this vacancy, please contact: mailbox-hr@cruk.cam.ac.uk.
Please quote reference SW43679 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
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